China (Mainland)
Tibolone / Liviella / Livial CAS NO.5630-53-5
- FOB Price: USD: 100.00-200.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
1(1-10)Kilogram1(10-25)Kilogram
- Product Details
Keywords
- Tibolone
- Liviella
- Livial
Quick Details
- ProName: Tibolone / Liviella / Livial
- CasNo: 5630-53-5
- Molecular Formula: C21H28O2
- Appearance: Off white crystalline powder
- Application: pharmaceutical industry
- DeliveryTime: 2-3 days after payment
- PackAge: (1). 1-10kg / foil bag (2). 25kg / d...
- Port: SHANGHAI
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99%
- Storage: Store in cool & dry place
- Transportation: 1.Air Courier Express Door to Door Ser...
- LimitNum: 1 Kilogram
- Related Substances: <0.1%
- Residue on Ignition: <0.1%
- Heavy Metal: <1ppm
- Valid Period: 24 months
Superiority
Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and APIs, Raw Steroid, Hormone products and other raw materials. Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.
Details
mf: c21h28o2
mw: 312.45
einecs: 227-069-1
mp 169 °c
refractive index 105 ° (c=0.54, ch2cl2/et2o)
storage temp. 2-8°c
usage a synthetic steroid with weak estrogenic, androgenic and progestogenic activity. a pharamceutical used in the treatment of menopausal syndrome
description:
1). tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for er alpha. it is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. it has also been investigated as a possible treatment for female sexual dysfunction.
2). tibolone (livial/liviella) is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for er alpha. tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. it has also been investigated as a possible treatment for female sexual dysfunction.
3). when estrogen levels are low tissues can slowly degenerate, as is experienced during menopause. in addition, low levels of estrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings, reduced sex drive and vaginal dryness.tibolone is broken down into three compounds which act in a similar way to the natural estrogen and progesterone found in the body. it restores plasma endorphin level in post-menopausal women and acts centrally to affect the thermo-regulatory system.
|
test items |
specification |
test results |
|
appearance |
white or almost white crystalline powder |
white crystalline powder |
|
loss on drying |
≦0.5% |
0.34% |
|
melting point |
139-141 °c |
139-140 °c |
|
(hplc)assay |
97-103.0% |
99.08% |
|
free acid |
0.5%max |
0.31% |
|
conclusion |
the aboye product conforms analysis standard |
conform |
1). tibolone is a synthetic hormone derived from the mexican yam.
2). tibolone is used to replace the body’s natural sex hormones. it is converted in the body into three other substances which act like the hormones oestrogen, progesterone or testosterone in different tissues.
3). tibolone acts like oestrogen in the brain (preventing flushes), bone (preventing bone loss) and vaginal tissue (preventing dryness and soreness).
4). tibolone also acts like progesterone in the womb to prevent overgrowth of the endometrium and subsequent bleeding. a woman who has not had a hysterectomy does not need to take a progesterone if she is taking tibolone.
5). tibolone has testosterone-like activity that appears to play a role in enhancing women’s mood and libido, although response is variable.
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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.
Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and APIs, Raw Steroid, Hormone products and other raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.
Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.
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