Binbo Biological Co., Ltd

Country:

China (Mainland)

Business Type: Lab/Research institutions

Ms.Yang

Tel: +86 186 2906 3126

Ms.Carmen

Tel: +86 18629063126

Mr.Alan

Tel: +86 13484623126

Ms.Serena

Tel: +86 18180906402

Fax: +86 29 82493158

City: Xi'an

Street: No.1 Fengcheng Road

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High Quality Dapagliflozin / Forxiga / Farxiga

High Quality Dapagliflozin / Forxiga / Farxiga CAS NO.461432-26-8

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Min.Order: 1 Kilogram
Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
Available Specifications:
1(1-10)Gram0.1/Gram1USD1(10-25)Gram0.2/Gram10USD

Product Details

Keywords

Dapagliflozin
Forxiga
Farxiga

Quick Details

ProName: High Quality Dapagliflozin / Forxiga /...
CasNo: 461432-26-8
Molecular Formula: C21H25ClO6
Appearance: white fine powder
Application: pharmaceutical industry
DeliveryTime: 2-3 days after payment
PackAge: (1). 1-10kg / foil bag (2). 25kg / d...
Port: SHANGHAI
ProductionCapacity: 1000 Kilogram/Month
Purity: 99%
Storage: Store in cool & dry place
Transportation: 1.Air Courier Express Door to Door Ser...
LimitNum: 1 Kilogram
Related Substances: <0.1%
Residue on Ignition: <0.1%
Heavy Metal: <1ppm
Valid Period: 24 months

Superiority

1.high purity

2.consistent quality

3.competitive price

4.fast shipping

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and APIs, Raw Steroid, Hormone products and other raw materials. Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.

Details

Product Name: Dapagliflozin

Synonyms: DAPAGLIFLOZIN;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol;2-(3-(4-Ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol;Bms 512148;D-Glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-ethoxyphenyl)methyl)phenyl)-, (1S)-;Dapagliflozin(BMS-512148);(2S,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol;1-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-1-deoxy-beta-D-glucopyranose (1S)-1,5-Anhydro-1-C-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol

CAS: 461432-26-8

MF: C21H25ClO6

MW: 408.8726

EINECS: 1592732-453-0

Product Categories: APIs;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs;Inhibitors

Mol File: 461432-26-8.mol

product name	Dapagliflozin
assay	99.0% to 101.0%	99.9%
melting point	----	----
loss on drying	0.5%max.	0.22%
sulphated ash	0.1%max.	0.05%
acidity	0.01m naoh<0.50ml	0.39

Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM, exhibiting 1200-fold selectivity over hSGLT1. Phase 3.

Dapagliflozin is not sensitive to hSGLT1 with a 1200-fold IC50. Dapagliflozin is 32-fold more potent than phlorizin against hSGLT2 but 4-fold less than phlorizin against hSGLT1. Dapagliflozin is highly selective versus GLUT transporters and displays 8–9% inhibition in protein-free buffer at 20 μM and virtually no inhibition in the presence of 4% bovine serum albumin. Dapagliflozin has good permeability across Caco-2 cell membranes and is a substrate for P-glycoprotein (P-gp) but not a significant P-gp inhibitor. Dapagliflozin is stable in rat, dog, monkey, and human serum at 10 μM. Dapagliflozin shows no inhibitory responses or induction to human P450 enzymes. The in vitro metabolic pathways Dapagliflozin are glucuronidation, hydroxylation, and O-deethylation.

It's a Animal Pharmaceuticals .

1. Air Courier Express Door to Door Service （DHL / TNT / FEDEX / UPS / EMS）

2. Normal Air

3. Normal Sea

Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and APIs, Raw Steroid, Hormone products and other raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.