CAS 107868-30-4 Anti Breast Cancer Powder Exemestane Aromasin CAS NO.107868-30-4
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- Min.Order: 1 Kilogram
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- Available Specifications:
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- Product Details
Keywords
- Exemestane
- Aromasin
- Exemestane Aromasin
Quick Details
- ProName: CAS 107868-30-4 Anti Breast Cancer Pow...
- CasNo: 107868-30-4
- Molecular Formula: C20H24O2
- Appearance: White crystalline powder
- Application: CAS 107868-30-4 Anti Breast Cancer Pow...
- DeliveryTime: 2-3 days after payment
- PackAge: (1). 1-10kg / foil bag (2). 25kg / d...
- Port: SHANGHAI
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99%
- Storage: Store in cool & dry place
- Transportation: 1.Air Courier Express Door to Door Ser...
- LimitNum: 1 Kilogram
- Related Substances: <0.1%
- Residue on Ignition: <0.1%
- Heavy Metal: <1ppm
- Valid Period: 24 months
Superiority
Exemestane Acatate Basic Info.
Details
Exemestane Basic information |
Product Name: | Exemestane |
Synonyms: | (8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione;ExeMestane (USP);ExeMestane(AroMasin);1,4-Androstadien-3,17-dione-6-Methylene-d2;ExeMestine;(8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione;ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione;PNU155971 |
CAS: | 107868-30-4 |
MF: | C20H24O2 |
MW: | 296.4 |
EINECS: | 1592732-453-0 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Pfizer compounds;Steroid and Hormone;API;Anti-cancer&immunity;Inhibitors;Active Pharmaceutical Ingredients;chiral;Antineoplastic (Hormonal) |
Mol File: | 107868-30-4.mol |
Exemestane Chemical Properties |
Melting point | 155.13°C |
storage temp. | Store at -20°C |
solubility | DMSO: ≥20mg/mL |
color | white to off-white |
InChIKey | BFYIZQONLCFLEV-DAELLWKTSA-N |
CAS DataBase Reference | 107868-30-4(CAS DataBase Reference) |
This drug has no noticeable effect on adrenal corticosteroids biosynthesis. Even when its concentration is over 600 times the concentration required to inhibit aromatase, it still has no noticeable effect the other enzymes in the corticosteroid production pathway.
This drug is absorbed quickly when taken orally and will affect food absorption. Its oral bioavailability is 42%. Postmenopausal women have a higher absorption rate than healthy test subjects. Patients reach peak blood concentration 2-4 hours after intake, and the peak lasts for an average of 1.2 hours, which is 2.9 hours shorter than healthy subjects. It mainly binds to Α1-acid glycoprotein and protein, and its overall binding rate to protein is 90%. It is mainly metabolized by the liver, the metabolite is inactive 17-Hydrecoxetron, and its clearing half-life is 24 hours. It is mostly excreted through urine and feces, which both account for 42% of the consumed amount.
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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.
Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and APIs, Raw Steroid, Hormone products and other raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.
Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.
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