China (Mainland)
high quality N-Methyl-D-aspartic acid CAS:6384-92-5 CAS NO.6384-92-5
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- Min.Order: 1 Kilogram
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- Product Details
Keywords
- N-Methyl-D-aspartic acid
- NMDA
- 6384-92-5
Quick Details
- ProName: N-Methyl-D-aspartic acid
- CasNo: 6384-92-5
- Molecular Formula: C14H17NO2
- Appearance: White crystalline powder
- Application: high quality N-Methyl-D-aspartic acid ...
- DeliveryTime: 2-3 days after payment
- PackAge: (1). 1-10kg / foil bag (2). 25kg / d...
- Port: SHANGHAI
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99%
- Storage: Store in cool & dry place
- Transportation: 1.Air Courier Express Door to Door Ser...
- LimitNum: 1 Kilogram
- Heavy Metal: <10ppm
- Limited Quantity: NA
- Valid Period: 24 MONTHS
Superiority
N-Methyl-D-aspartic acid
Chemical Name:(2R)-2-(methylamino)butanedioic acid
CAS No: 6384-92-5
Formula: C5H9NO4
Molecular mass: 147.13 g/mol
Assay：99%
By name: N-Methyl-D-aspartic acid
Description
N-Methyl-D-Aspartic acid (NMDA) is a synthetic agonist of the NMDA receptor that mimics the binding action of the endogenous ligand glutamate. The NMDA receptor is a voltage-gated ion channel closely involved in memory, in spatial learning and perturbing the normal behavior of this receptor system with NMDA exposure has facilitated elucidation of NMDA receptor-mediated activities.
NMDA is a glutamate-like excitatory substance and is a particularly potent excitant. NMDA binds to NMDA-receptor and interacts with it. This interaction causes a conformational change in the receptor or associated membrane molecules, which opened pores to allow extracellular sodium ions to flow down their electrochemical gradient and depolarise the cell. However, NMDA is proved to be a poor substrate for the uptake transporters, suggesting that the excitatory effect could not be an indirect consequence of glutamate uptake. Besides that, NMDA is found to increase intracellular calcium and release arachidonic acid, both of which generate oxygen radicals, subsequently inducing neuronal death.
Details
| Product Name: | N-Methyl-D-aspartic acid |
| Synonyms: | n-methylaspartate;n-methyl-d-aspartate;n-methyl-d-asparticaci;H-D-MEASP-OH;H-D-MEASP-OH HCL;[R]-2-[METHYLAMINO]SUCCINIC ACID;N-ALPHA-METHYL-D-ASPARTIC ACID;N-ALPHA-METHYL-D-ASPARTIC ACID HYDROCHLORIDE |
| CAS: | 6384-92-5 |
| MF: | C5H9NO4 |
| MW: | 147.13 |
| EINECS: | 227-012-0 |
| Product Categories: | Glutamate receptor;Glutamate;amino acids;Inhibitors;Pyridines |
| Mol File: | 6384-92-5.mol |
| N-Methyl-D-aspartic acid Chemical Properties |
| Melting point | 187-192 °C |
| alpha | -28 º (c=1, HCl 6N) |
| refractive index | -15 ° (C=2, H2O) |
| storage temp. | Store at RT. |
| form | solid |
| color | white |
| Water Solubility | slightly soluble |
| Sensitive | Hygroscopic |
| Merck | 14,6662 |
| CAS DataBase Reference | 6384-92-5(CAS DataBase Reference) |
| Safety Information |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | CI9457000 |
| F | 10 |
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Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.
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